Pubblicazioni

M. Krampera, O. Perbellini, A. Maggioni, F. Scognamiglio, G. Todeschini, G. Pizzolo.
Flow-cytometric detection of minimal residual disease in adult acute lymphoblastic leukemia. Haematologica 86(3): 322-323, 2001.

M. Krampera, S. Glennie, R. Laylor, J. Dyson, D. Scott, E. Simpson, F. Dazzi.
Bone marrow mesenchymal stem cells inhibit the response of naïve and memory antigen-specific T cells to their cognate peptide.
Blood 101: 3722-3729, 2003.

M.T. Scupoli, F. Vinante, M. Krampera, C. Vincenzi, G. Nadali, F. Zampieri, M.A. Ritter, E. Eeren, F. Santini, G. Pizzolo.
Thymic epithelial cells promote survival of human T-cell acute lymphoblastic leukemia blasts: the role of interleukin-7.
Haematologica 88: 1229-37, 2003.

M. Krampera, A. Vitale, C. Vincenzi, O. Perbellini, A. Guarini, L. Annino, G. Todeschini, A. Camera, F. Fabbiano, G. Fioritoni, F. Nobile, R. Szydlo, F. Mandellli, R. Foà, G. Pizzolo.
Outcome prediction by immunophenotypic minimal residual disease detection in adult T cell acute lymphoblastic leukemia. Br J Haematol 120(1): 74-79, 2003.

G.M. Bendle, A. Holler, L.K. Pang, S. Hsu, M. Krampera, E. Simpson, H.J. Stauss.
Induction of unresponsiveness limits tumor protection by adoptively transferred MDM2-specific cytotoxic T lymphocytes. Cancer Res 64: 8052-8056, 2004.

M. Krampera, A. Pasini, A. Rigo, M.T. Scupoli, C. Tecchio, G. Malpeli, A. Scarpa, F. Dazzi, G. Pizzolo, F. Vinante.
HB-EGF/HER-1 signalling in bone marrow mesenchymal stem cells: inducing cell expansion and reversibly preventing multi-lineage differentiation.
Blood 106:59-66, 2005

M. Krampera, L. Cosmi, R. Angeli, A. Pasini, F. Liotta, A. Andreini, V. Santarlasci, B. Mazzinghi, G. Pizzolo, F. Vinante, P. Romagnani, E. Maggi, S. Romagnani, F. Annunziato.
Role of the IFN-gamma in the immunomodulatory activity of human mesenchymal stem cells.
Stem Cells 24:386-398, 2006.

A. Vitale, A. Guarini, C. Ariola, M. Mancini, C. Mecucci, A. Cuneo, F. Pane, G. Saglio, G. Cimino, A. Tafuri, G. Meloni, F. Fabbiano, A. Recchia, M.G. Kropp, M. Krampera, N. Cascavilla, F. Ferrara, A. Romano, P. Mazza, C. Fozza, F. Paoloni, M. Vignetti, R. Foà.
Adult T-cell acute lymphoblastic leucemia: biologic profile at presentation and correlation with response to induction treatment in patients enrolled in the GIMEMA LAL 0496 protocol. Blood 107;473-479, 2006.

M. Krampera, A. Pasini, G. Pizzolo, L. Cosmi, S. Romagnani, F. Annunziato.
Regenerative and immunomodulatory potential of mesenchymal stem cells.
Curr Opin Pharmacol 6:435-441, 2006 

M. Krampera, G. Pizzolo, G. Aprili, M. Franchini.
Mesenchymal stem cells for bone, cartilage, tendon and skeletal muscle repair.
Bone 39:678-683, 2006 

M. Krampera, G. Pizzolo.
Le cellule staminali mesenchimali.
Seminari di Ematologia Oncologica 3(2):131-153, 2006

M. Krampera, O. Perbellini, C. Vincenzi, F. Zampieri, A. Pasini, M.T. Scupoli, A. Guarini, S. De Propris, E. Coustan-Smith, A. Vitale, D. Campana, R. Foà, G. Pizzolo.
Methodological approach to minimal residual disease detection by flow cytometry in adult B-lineage acute lymphoblastic leukemia. Haematologica 91;1109-1112, 2006.

G. Rigotti, A. Marchi, M. Galiè, G. Baroni, D. Benati, M. Krampera, A. Pasini, A. Sbarbati.
Clinical treatment of radiotherapy tissue damages by lipoaspirates transplant: a healing process mediated by adipose-derived adult stem cells (ASCs).
Plast Reconstr Surg, 119:1409-1422. 2007.

M. Krampera, S. Marconi, A. Pasini, M. Galiè, F. Mosna, M. Tinelli, L. Lovato, E. Anghileri, A. Andreini, G. Pizzolo, A. Sbarbati, B. Bonetti.
Induction of neural-like differentiation in human mesenchymal stem cells derived from bone marrow, fat, spleen and thymus.
Bone 40;382-390, 2007.

M.T. Scupoli, O. Perbellini, M. Krampera, F. Vinante, F. Cioffi, G. Pizzolo.
Interleukin-7 requirement for survival of T-cell acute lymphoblastic leukemia and human thymocytes on bone marrow stroma. Haematologica 92;264-266, 2007.

M. Krampera, S. Sartoris, L. Cosmi, A. Pasini, R. Angeli, F. Liotta, M. Tinelli, A. Andreini, F. Mosna, E. Rebellato, M.G. Testi, V. Santarlasci, G. Pizzolo, G. Tridente, E. Maggi, S. Romagnani, F. Annunziato.
Immune regulation by mesenchymal stem cells derived from adult spleen and thymus.
Stem Cells and Development 16;797-810, 2007.

M. Krampera, M. Franchini, G. Pizzolo, G. Aprili.
Mesenchymal stem cells: from biology to clinical use.
Blood Transfusion 5;120-129, 2007 

F. Bifari, V. Lisi, E. Mimiola, A. Pasini, M. Krampera.
Immunological properties of mesenchymal stem cells.
Transfusion Medicine and Hemotherapy 2008;35:194-204 

D. Peroni, I. Scambi, A. Pasini, V. Lisi, F. Bifari, M. Krampera, G. Rigotti, A. Sbarbati, M. Galiè.
Stem molecular signature of adipose-derived stromal cells.
Exp Cell Research 314:603-615, 2008.

E. Anghileri, S. Marconi, A. Pignatelli, P. Cifelli, M. Galié, A. Sbarbati, M. Krampera, O. Belluzzi, B. Bonetti.
Neuronal differentiation potential of human mesenchymal stem cells.
Stem Cells and Development 17:909-916, 2008.

M. Galiè, G. Konstantinidou, D. Peroni, I. Scambi, C. Marchini, V. Lisi, M. Krampera, P. Magnani, F. Merigo, M. Montani, F. Boschi, P. Marzola, R. Orrù, P. Farace, A. Sbarbati, A. Amici.
Mesenchymal stem cells share molecular signature with mesenchymal tumor cells and favors the early tumor growth in syngeneic mice.
Oncogene 27: 2542-2551, 2008.

F. Liotta, R. Angeli, L. Cosmi, L. Filì, C. Manuelli, F. Frosali, B. Mazzinghi, L. Maggi, A. Pasini, V. Lisi, V. Santarlasci, L. Consoloni, P. Romagnani, P. Parronchi, M. Krampera, E. Maggi, S. Romagnani, F. Annunziato.
TLR3 and TLR4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signalling.
Stem Cells 26(1):279-89, 2008.

M.T. Scupoli, M. Donadelli, F. Cioffi, M. Rossi, O. Perbellini, G. Malpeli, S. Corbioli, F. Vinante, M. Krampera, M. Palmieri, A. Scarpa, C. Ariola, R. Foà, G. Pizzolo.
Bone marrow stromal cells and the upregulation of interleukin-8 production in human T-cell acute lymphoblastic leukemia through the CXCL12/CXCR4 axis and the NF-kB and JNK/AP-1 pathways.
Haematologica 93:524-532, 2008.

F. Bifari, I. Decimo, C. Chiamulera, E. Bersan, G. Malpeli, J. Johanson, V. Lisi, B. Bonetti, G. Fumagalli, G. Pizzolo, M. Krampera.
Novel stem/progenitor cells with neuronal differentiation potential reside in the leptomeningeal niche.
J Cell Mol Med 13(9B):3195-208, 2009.

D. Gemmati, M. De Mattei, L. Catozzi, M. Della Porta, M.L. Serino, C. Ambrosio, A. Cuneo, S. Friso, M. Krampera, E. Orioli, G. Zeri, A. Ongaro. DHFR 19-bp insertion/deletion polymorphism and MTHFR C677T in adult acute lymphoblastic leukemia: is the risk reduction due to intracellular folate unbalancing? Am J Hematol 84:526-529, 2009.

G. Constantin, S. Marconi, B. Rossi, S. Angiari, A. Pasini, M. Galiè, B. Gini, F. Bifari, A. Sbarbati, M. Krampera, B. Bonetti.
Adipose-derived mesenchymal stem cells ameliorate chronic EAE by immunosuppression and neuroregeneration.
Stem Cells 27:2624-2635, 2009.

L. Sensebé, M. Krampera, H. Schrezenmeier, P. Bourin, R. Giordano.
Mesenchymal stem cells for clinical application.
Vox Sanguinis 98:93-107, 2010

F. Giannone, G. Malpeli, V. Lisi., S. Grasso, P. Shukla, D. Ramarli, V. Monsurrò, S. Sartoris, M. Krampera, E. Amato, G. Tridente, M. Colombatti, M. Parenti, G. Innamorati.
The puzzling uniqueness of the heterotrimeric G15 protein and its potential beyond hematopoiesis.
Journal of Molecular Endocrinology 2010;44(5):259-269.

M. Martini, M.G. Testi, M. Pasetto, M.C. Picchio, G. Innamorati, M. Mazzocco, S. Ugel, S. Cingarlini, V. Bronte, P. Zanovello, M. Krampera, F. Mosna, T. Cestari, A.P. Riviera, N. Brutti, O. Barbieri, L. Matera, G. Tridente, M. Colombatti, S. Sartoris.
IFN-alpha- Mediated Upmodulation of MHC Class I Expression Activates Tumor-Specific Immune Response in a Mouse Model of Prostate Cancer.
Vaccine 2010;28(20):3548-3557.

F. Bifari, L. Pacelli, M. Krampera.
Immunological properties of embryonic and adult stem cells
World J Stem Cells 2010 2(3):50-60.

F. Mosna, L. Sensebé, M. Krampera.
Human bone-marrow and adipose tissue mesenchymal stem cells: a user’s guide.
Stem Cells and Development 2010;19:1449-70.

F. Mosna, F. Annunziato, G. Pizzolo, M. Krampera.
Cell therapy for cardiac regeneration after myocardial infarct: which cell is the best?
Cardiovascular & Hematological Agents in Medicinal Chemistry (former Current Medicinal Chemistry - Cardiovascular & Hematological Agents) 2010;8:227-43.

S. Sartoris, M. Mazzocco, M. Tinelli, M. Martini, F. Mosna, V. Lisi, S. Indraccolo, L. Moserle, T. Cestari, A.P. Riviera, F. Bifari, G. Tridente, G. Pizzolo, M. Krampera.
Efficacy assessment of interferon-alpha-engineered mesenchymal stromal cells in a mouse plasmacytoma model.
Stem Cells and Development 2011;20:709-19.

F. Dazzi, M. Krampera.
Mesenchymal stem cells and autoimmune diseases. In 'Mesenchymal Stem Cells: basic in clinical aspects' 
 Best Pract Res Clin Haematol 2011;24:49-57.

M. Krampera. Mesenchymal stromal cells: more than inhibitory cells. Leukemia 2011;25:565-566.

M.A. Cassatella, F. Mosna, A. Micheletti, V. Lisi, N. Tarmassia, C. Cont, F. Calzetti, M. Pellettier, G. Pizzolo, M. Krampera. TLR-3-activated human mesenchymal stromal cells significantly prolong the survival and function of neutrophils. Stem Cells 2011;29:1001–1011.

M. Krampera. Mesenchymal stromal cell ‘licensing’: a multistep process. Leukemia 2011;25:1408-1414.

F. Mosna, G. Pizzolo, M. Krampera. Cellule staminali e rigenerazione cardiaca. Seminari di Ematologia Oncologica 2, 2011.

A.H. Nwabo Kamdje, F. Mosna, F. Bifari, V. Lisi, O.Perbellini, M.T. Scupoli, G. Pizzolo, M. Krampera.
Notch-3 and Notch-4 signaling rescue from apoptosis human B-lineage acute lymphoblastic leukemia cells in contact with human bone marrow-derived mesenchymal stromal cells. Blood 2011;118:380-389.

I. Decimo , F. Bifari, M. Krampera, G. Fumagalli. Neural stem cell niches in health and diseases. Current Pharmaceutical Design 2011 (in press).

M. Ricciardi, L. Pacelli, G. Bassi, F. Bifari, F. Mosna, M. Krampera. Mesenchymal stem cell isolation and expansion methodology. In: Stem Cells And Cancer Stem Cells: Therapeutic Applications in Disease and Injury. Springer Editor, 2011. 

I. Decimo, F. Bifari, F.J. Rodriguez, S. Dolci, V. Lavarini, S. Pretto, S. Vasquez, G. Malpeli, M. Sciancalepore, A. Montalbano, M. Krampera, G. Fumagalli. Nestin- and DCX-positive cells reside in adult spinal cord meninges and participate to injury-induced parenchymal reaction. Stem Cells 2011;29:2062-2076.

A.H. Nwabo Kamdje, M. Krampera. Notch signaling in acute lymphoblastic leukemia: any role for stromal microenvironment? Blood 2011;118:6506-6514. 

G. Bassi, L. Pacelli, R. Carusone, J. Zanoncello, M. Krampera. Adipose-derived stromal cells (ASCs). Transfusion and Apheresis Science 2012; 47:193-198. 

L. Sensebé, K. Tarte, J. Galipeau, M. Krampera, I. Martin, D.G. Phinney, Y. Shi, on behalf of MSC Committee of International Society for Cellular Therapy (ISCT). The Mesenchymal Stromal Cell (MSC) paradigm: human adult MSC are not prone to acquire advantageous tumor-prone chromosomal aberrations. Cell Stem Cell 2012;10:9.

M. Ricciardi, G. Malpeli, F. Bifari, G. Bassi, L. Pacelli, A.H. Nwabo Kamdje, M. Chilosi, M. Krampera. Comparison of epithelial differentiation and immune regulatory properties of mesenchymal stromal cells derived from human lung and bone marrow. PLoS One 2012;7(5):e35639.

I. Decimo, G. Fumagalli, V. Berton, M. Krampera, F. Bifari. Meninges: from protective membrane to stem cell niche. Am J Stem Cell 2012;1(2):92-105. 

A.H. Nwabo Kamdje, G. Bassi, L. Pacelli, G. Malpeli, E. Amati, I. Nichele, G. Pizzolo, M. Krampera. Role of stromal cell-mediated Notch signaling in B-CLL cell survival and resistance to chemotherapy. Blood Cancer Journal 2012; 2(5):e73.

P.F. Seke Etet, L. Vecchio, P. Bogne Kamga, E.N. Nukenine, M. Krampera, A.H. Nwabo Kamdje. Normal hematopoiesis and hematologic malignancies: role of canonical Wnt signaling pathway and stromal microenviroment. BBA Review on Cancer 2013:1835:1-10.

M. Ricciardi, M. Krampera, M. Chilosi. Quantitative Fluorescence In situ Hybridization (Q-FISH) on paraffine embedded tissue. In: Aging and Stem Cells. Methods Mol Biol. 2013;976:167-173, Springer Editor. 

M. Krampera, J. Galipeau, Y. Shi, F. Dazzi, K. Le Blanc, K. Tarte, L. Sensebé, on behalf of the MSC Committee of the International Society for Cellular Therapy (ISCT). Immunological characterization of Multipotent Mesenchymal Stromal Cells. The International Society for Cellular Therapy working proposal.  Cytotherapy 2013;15(9):1054-1061.

I. Nichele, A. Zamò, A. Bertolaso, F. Bifari, M. Tinelli, M. Franchini, R. Stradoni, F. Aprili, G. Pizzolo, M. Krampera. VR09: an EBV-positive lumphoblastoid cell line with in vivo characteristics of diffuse large B cell lymphoma of activated B-cell type. Plos One 2012; 7(12): e52811. 

C. Cavallini, O. Lovato, A. Bertolaso, L. Pacelli, E. Zoratti, E. Zanolin, M. Krampera, A. Zamò, C. Tecchio, M.A. Cassatella, G. Pizzolo, M.T. Scupoli. The TNF-family cytokine TL1A inhibits the proliferation of human activated B cells. Plos One 2013;8(4):e60136.

C. Menard, L. Pacelli, G. Bassi, J. Dulong, F. Bifari, I. Bezier, J. Zanoncello, M. Ricciardi, M. Latour, P. Bourin, H. Schrezenmeier, L. Sensebé, K. Tarté, M. Krampera. Clinical-grade mesenchymal stromal cells produced under various GMP processes differ in their immunomodulatory properties: standardization of immune quality controls. Stem Cells and Development 2013;22(12):1789-1801.

L. Vecchio, P.F. Seke Etet, M.J. Kipanyula, M. Krampera, A.H. Nwabo Kamdje. Importance of epigenetic changes in cancer etiology, pathogenesis, clinical profiling, and treatment: what can be learned from hematologic malignancies? BBA Review on Cancer 2013;1836(1):90-104.

D.G. Phinney, J. Galipeau, M. Krampera, I. Martin, Y. Shi, L. Sensebé. MSCs: science and trials. Nature Medicine 2013;19(7):812.

M. Di Trapani, G. Bassi, M. Ricciardi, E. Fontana, F. Bifari, L. Pacelli, L. Giacomello, M. Pozzobon, F. Feron, P. De Coppi, P. Anversa, G. Fumagalli, I. Decimo, C. Menard, K. Tarte, M. Krampera. Comparative study of immune regulatory properties of stem cells derived from different tissues. Stem Cells and Development 2013;22:2990-3002.

W. Zhao, D.G. Phinney, D. Bonnet, M. Dominici, M. Krampera.  Mesenchymal stem cell biodistibution, migration, and homing in vivo. Stem Cells Int. 2014;2014:292109.

A.H. Nwabo Kamdje, P.F. Seke Etet, L. Vecchio, J.M. Muller, M. Krampera, K.E. Lukong. Signaling pathway in breast cancer: therapeutic targeting of the microenvironment. Cell Signalling 2014;26(12):2843-2856.

A.H. Nwabo Kamdje, P.F. Seke Etet, L. Vecchio, R. Simo Tagne, J Mbo Amvene, JM Muller, M. Krampera, K.E. Lukong. New targeted therapies for breast cancer: a focus on tumor microenvironmental signals and chemoresistant breast cancers. World J Clin Cases 2014;2(12):769-786.

G. Bassi, F. Guilloton, C. Menard, M. Di Trapani, F. Deschaseaux, L. Sensebé, H. Schrezenmeier, R. Giordano, P. Bourin,  M. Dominici, K. Tarte, M. Krampera. Effects of a ceramic biomaterial on immune modulatory properties and differentiation potential of human mesenchymal stromal cells of different origin. Tissue Engineering 2015;21(3-4):767-781.

A. Mercuri, E. Cannata, O. Perbellini, C. Cugno, R. Balter, A. Zaccaron, G. Tridello, G. Pizzolo, M. De Bortoli, M. Krampera, M. Cipolli, S. Cesaro. Immunophenotypic analysis in patients suffering from Shwachmann-Bodian-Diamond Syndrome. Eur J Haematol 2015;95(4):308-15.

J. Galipeau, M. Krampera. The challenge of defining MSC potency assays and their potential use as release criterion. Cytotherapy 2015;17(2):125-127.

M. Ricciardi, M. Zanotto, G. Malpeli, G. Bassi, O. Perbellini, M. Chilosi, F. Bifari, M. Krampera. Epithelial-to-Mesenchymal Transition (EMT) induced by inflammatory priming elicits mesenchymal stromal cell-like immune modulatory properties in cancer cells. Br J Cancer 2015;112:1067-1075.

E. Zanchetta, E. Guidi, G. Della Giustina, M. Sorgato, M. Krampera, G. Bassi, R. Di Liddo, G. Lucchetta, M.T. Conconi, G. Brusatin. Injection Moulded polymeric micropatterns for bone regeneration study. ACS Appl Mater Interfaces 2015;7(13):7273-81.

M. Bonifacio, G. Binotto, E. Maino, E. Calistri, L. Marin, L. Scaffidi, L. Frison, F. De Marchi, M. Krampera, G. Semenzato, R. Fanin, A. Ambrosetti, M. Tiribelli. Imatinib-treated chronic myeloid leukemia patients with discordant response between cytogenetics and molecular tests at 3 and 6 month time-points have a reduced probability of subsequent optimal response. Haematologica 2015;100(8):e299-301.

O.E. Simonson, D. Mougiakakos, N. Heldring, G. Bassi, H.J. Johansson, R. Jitschin, M. Dalén, S. Rodin, M. Corbascio, S. EL Andaloussi, O. PB Wiklander, J.Z. Nordin, J. Skog, C. Romain, T. Koestler, L. Hellgren-Johansson, P. Schiller, P-O. Joachimsson, H. Hägglund, M. Mattsson, J. Lehtiö, O.R. Faridani, R. Sandberg, O. Korsgren, M. Krampera, D.J. Weiss, K-H. Grinnemo, K. Le Blanc. Treatment of severe acute respiratory distress syndrome with allogeneic bone marrow-derived mesenchymal stromal cells. Stem Cells Translational Medicine 2015;4(10):1199-213.

F. Bifari, V. Berton, A. Pino, M. Kusalo, G. Malpeli, M. Di Chio, E. Bersan, E. Amato, A. Scarpa, M. Krampera, G. Fumagalli, I. Decimo. Meninges harbor cells expressing neural precursor markers during development and adulthood. Frontiers in Cellular Neuroscience 2015;9:383.

Galipeau J, Krampera M, Barrett J, Dazzi F, Deans RJ, DeBruijn J, Dominici M, Fibbe WE, Gee AP, Gimble JM, Hematti P, Koh MB, LeBlanc K, Martin I, McNiece IK, Mendicino M, Oh S, Ortiz L, Phinney DG, Planat V, Shi Y, Stroncek DF, Viswanathan S, Weiss DJ, Sensebe L. International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials. Cytotherapy 2016;18(2):151-9.

P.K. Takam, G. Bassi, A. Cassaro, M. Midolo, M. Di Trapani, F. Canella, R. Carusone, A. Gatti, F. Resci, O. Perbellini, M. Gottardi, M. Bonifacio, A.H. Nwabo Kamdje, A. Ambrosetti, M. Krampera. Notch signaling drives bone marrow stromal cell-mediated chemoresistance in acute myeloid leukemia. Oncotarget 2016;7(16):21713-27.

M. Di Trapani, G. Bassi, M. Midolo, A. Gatti, P. Takam, A. Cassaro, R. Carusone, A. Adamo, M. Krampera. Differential and transferable modulatory effects of mesenchymal stromal cell-derived extracellular vesicles on T, B and NK cell functions. Scientific Reports 2016;6:24120.

G. Malpeli, S. Barbi, S. Zupo, G. Tosadori, G. Scardoni, A. Bertolaso, S. Sartoris, S. Ugel, A. Adamo, M. Krampera, M.T. Scupoli, C.M. Croce, A. Scarpa. Identification of microRNAs implicated in the late differentiation stages of normal B cells suggest a central role for miRNA targets ZEB1 and TP53. Oncotarget 2016 (in press).